Drug therapy in order to kill the myeloma cells is the main therapy for myeloma patients who need treatment. Some of the drugs which are most recommended for the treatment of myeloma are:
Carfilzomib (Kyprolis): This medication is given intravenously (IV). It is recommended in order to treat myeloma patients who have received at least a couple of other treatments (including Velcade and a drug such as thalidomide or Revlimid) and the myeloma progressed soon following the last treatment.
Pomalidomide (Pomalyst): This drug is given by mouth. pomalidomide is recommended in order to treat myeloma patients who have received at least two treatments (like Revlimid and Velcade) and the myeloma progressed soon after the last treatment.
Melphalan (Alkeran): This is a type of chemotherapy drug recommended in order to treat myeloma patients. Melphalan can be combined with the other drugs such as Thalomid, Velcade or Revlimid.
Bortezomib (Velcade): It is given intravenously (IV) or subcutaneously. It is recommended in order to treat myeloma patients. Bortezomib is also being studied in clinical trials together with the other drugs such as Revlimid.
Thalidomide (Thalomid): It is given by mouth. Thalidomide is recommended with the dexamethasone and another agent, such as Velcade in order to treat newly diagnosed myeloma patients. The use of thalidomide together with the other drugs is also being studied.
Lenalidomide (Revlimid): This is a drug like thalidomide and is given by mouth. It is safer and works better for myeloma patients. Lenalidomide is recommended with the dexamethasone in order to treat myeloma patients who have already had at least one other type of treatment.
Aranesp (darbepoetin alfa) and Procrit (epoetin alfa): These are drugs that may increase the number of red cells and can help with anemia. These medications can decrease the requirement for the blood transfusions. The benefit of these drugs to treat people who have different types of cancer is under study. Discuss with your doctor about all the benefits as well as risks.
Velcade and liposomal doxorubicin (Doxil): These are drugs which hold the approval in order to treat myeloma patients who have relapsed or who have not responded to any kind of one other treatment.
Bisphosphonates: This includes drugs such as pamidronate (Aredia) and zoledronic acid (Zometa) and can help in lessen the effects of the bone disease in patients with the myeloma by decreasing pain and decreasing the likelihood of a fracture. It is necessary to know about the side effects of these drugs. Interact with your healthcare provider about the benefits as well as risks.
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