What is Voriconazole:
Voriconazole is an antifungal medication, which works by affecting fungal metabolism and fungal cell membranes. It is in the triazole family of medications.
Uses of Voriconazole 200mg:
Voriconazole is used to treat invasive aspergillosis and candidiasis and fungal infections caused by Scedosporium and Fusarium species, which may occur in immunocompromised patients, including people undergoing allogeneic bone marrow transplant (BMT), who have hematologic cancers or who undergo organ transplants.
Voriconazole is also used in order to prevent fungal infection in people as they undergo Bone Marrow Transplant.
Voriconazole can be also recommended for the treatment of CNS fungal infections transmitted by epidural injection of contaminated steroids.
Side Effects of Voriconazole Injection:
Some common side effects include:
Fever
Sweating
Feel faint
Nausea
Itching
Headache
Skin rash
Mouth sore
Blurred vision
Chest tightness
Trouble breathing
Feels like your heart is beating fast.
Use of this medication during pregnancy may result in harm to the baby.
The existence of Voriconazole is 50 mg and also 200 mg tablets. During the first days of therapy, it can also be given by intravenous (I.V. in the veins) injections. The Voriconazole injections will be given over a 1 to 2 hour period, likely by a nurse at the clinic.
The dose of voriconazole will depend on your weight and on the other drugs you are taking. Usual dosage should be specified as Voriconazole 200 mg twice daily. This dose may need to be adjusted by your healthcare provider in order to meet your needs.
Voriconazole tablets should be taken on an empty stomach. Take your dose at least 1 hour before or 2 hours after a meal.
How it is helpful for the treatment of HIV:
Voriconazole is a new antifungal with proven efficacy for treating the candidosis and invasive aspergillosis as well as other mould infections, like those caused by Fusarium and Scedosporium spp. The drug is generally well tolerated. Voriconazole is an azole antifungal agent. The major action of voriconazole is the inhibition of fungal cytochrome P-450-mediated 14 alpha-lanosterol demethylation, an essential step in fungal ergosterol biosynthesis. When accumulated 14 alpha-methyl sterols correlated with the subsequent loss of ergosterol in the fungal cell wall it may be responsible for the antifungal activity of voriconazole.
Voriconazole Injection is an Antiretroviral medication or HIV medication that helps in the prevention of HIV in order to multiply (making copies of itself), So that as a result, an existing amount of HIV in the body reduces. (called the viral load). Less existence of HIV in the body gives the immune system a chance to recover and produce more CD4 cells.
The PRICE of Voriconazole is quite affordable. A respective patient can purchase it through any authorized pharmaceutical company.
People who have hereditary intolerance for galactose, Lapp lactase deficiency, or glucose-galactose malabsorption should not take this drug. This medication should be used with a lot of caution in people with arrhythmias or long QT.
There is no need in the dose adjustment for renal impairment or advanced age, but children seem to clear voriconazole 200 mg faster than adults and drug levels may need monitoring.